To stop the Strong I Off-Tackle run you have to be absolutely balls out aggressive. Especially if you are outleveled. A tactic would be a goaline formation which is 4-4 with 1 S and 2 CB's. With a strong side shift. And a run focus to stakc the box. And blitz at least 2 guys. Another is a 4-3 strong side shift cover 1 to bring the SS up with a run focus. This basically puts the SS up with the MLB/LOLB maybe slightly back. And blitz the hell out of them. I would blitz the LOLB/MLB and maybe the SS but let the ROLB do his thing because he will come over to the strong side and get the RB if he broke thru the wall. You can blitz the SS. Alot of teams are predictable and usually run the play alot.
Note: If the team throws some out of the Strong I don't be this aggressive.
Note: If the team throws some out of the Strong I don't be this aggressive.