totally possible!
http://glb.warriorgeneral.com/game/player.pl?player_id=44614494 WL seasons, top 5 in DMVP in 3 of those seasons. The other season I tried something too different and screwed all of the stats for my pass-rushers.
24+ pass deflections in each season. Which doesn't sound like a ton, but in the WL, it's absolutely a difference maker. Consistently top 10 in deflections, and always first DL by a landslide.
If you're actually thinking of trying again and want to talk builds, shoot me a PM.
But the system is at least as important as the build for this type of player to be effective, so there is that as well.